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Nutrac�utico � base de urucum pode ser?? um aliado no combate � gordura no f�gado.
Produto foi obtido por meio de tecnologia patenteada pela Unicamp e j� est�?? a caminho das prateleiras.
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Nutrac�utico � base de urucum?? pode ser usado para combater ac�mulo de gordura no f�gado � 
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Pesquisadores da Unicamp, em parceria com?? uma startup criada por ex-alunos da universidade, desenvolveram um nutrac�utico � base de urucum que pode ser um aliado no?? combate � gordura no f�gado. Criado a partir do extrato da semente da fruta, o produto foi obtido por meio?? de uma tecnologia patenteada pela institui��o de ensino e j� est� a caminho das prateleiras.
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?? O que � um nutrac�utico? Resumidamente, � uma categoria de suplemento alimentar feita a partir de alimentos �?? como o urucum � que t�m compostos ben�ficos para a sa�de. O foco do novo produto desenvolvido em Campinas (SP)?? s�o pessoas com obesidade ou sobrepeso, fatores de risco para doen�as hep�ticas.
�Nossa sociedade passa por um momento muito cr�tico que,?? al�m das limita��es nutricionais por raz�es socioecon�micas, ocorrem tamb�m quest�es derivadas pela qualidade nutricional em fun��o do estilo de vida?? e do consumo de alimentos ultraprocessados. O surgimento de suplementos nutricionais, de origem natural, est� em crescimento acelerado, suprindo diversas?? defici�ncias nutricionais, numa posi��o principalmente preventiva�, destaca o co-fundador da startup, Eduardo Aledo.
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?? Por?? que o urucum? A escolha da fruta n�o foi ao acaso. Segundo Aledo, a pesquisa partiu de uma busca por?? bioativos presentes na biodiversidade brasileira, e o urucum ganhou destaque pela a��o a��o antioxidante e anti-inflamat�ria j� mapeada por pesquisas?? anteriores.
�Em 2013, foi realizada uma pesquisa de mestrado utilizando-se um processo chamado extra��o por di�xido de carbono supercr�tico da semente?? de urucum que, juntamente com o corante, cont�m um �leo muito rico com dois bioativos chamados tocotrienol e geranilgeraniol, com?? propriedades muito interessantes e de efeito sin�rgico�, afirma.
Com o �leo da semente de urucum dispon�vel, era necess�rio entender como o?? produto poderia agir para beneficiar pacientes. Foi ent�o que a Unicamp foi acionada, e a equipe do professor M�rio Roberto?? Mar�stica J�nior, da Faculdade de Engenharia de Alimentos, deu in�cio �s pesquisas.
�A empresa associada chegou com um problema para a?? gente. Eles tinham um extrato e chegaram com o problema de saber a aplica��o biol�gica disso. E n�s, atrav�s da?? composi��o, produzimos um estudo em conjunto que resultou em propriedades importantes contra a obesidade�, explica Mar�stica.
Professor M�rio Roberto Mar�stica J�nior,?? da Faculdade de Engenharia de Alimentos da Unicamp � 
: Pedro Amatuzzi/Inova Unicamp
?? Como o estudo foi feito? Para a?? realiza��o do estudo, os pesquisadores induziram uma dieta hiperlip�dica em animais obesos para simular a diabete tipo 2 e, em?? seguida, passaram a administrar o �leo da semente de urucum. Paralelamente, um segundo grupo de animais n�o recebeu nenhum tratamento.
�Os?? animais que receberam o �leo de urucum tiveram uma melhora na resposta nos par�metros hep�ticos em rela��o �queles que n�o?? foram tratados. Ent�o o bioativo foi de import�ncia para melhorar a esteatose hep�tica em diabete tipo 2 induzida por dieta?? hiperlip�dica�, diz o professor.
Ainda de acordo com Mar�stica, a principal inova��o do nutrac�utico � a composi��o, com ativos carotenoides e?? terpenoides. Al�m disso, o produto � obtido por vias naturais, em um processo de extra��o limpa, e pode ser uma?? alternativa a medicamentos tradicionais com efeitos colaterais.
"Esse composto � obtido por vias naturais, por um processo de extra��o limpa; n�o?? tem contraindica��es porque n�o foram observados efeitos toxicol�gicos nas doses estudadas; e oferece um tratamento contra uma doen�a de alto?? impacto no mundo hoje, via um nutrac�utico brasileiro", destaca.
Nutrac�utico � comercializado por startup criada por ex-alunos da Unicamp � 
:?? Eduardo Aledo/Arquivo pessoal
?? Quais s�o os pr�ximos passos? Eduardo Aledo, co-fundador da empresa-filha da Unicamp respons�vel pela comercializa��o do nutrac�utico,?? afirma que o produto est� atualmente em processo de obten��o de registro como suplemento industrial na Ag�ncia Nacional de Vigil�ncia?? Sanit�ria (Anvisa).
�H� outro segmento conhecido como canal magistral, ou de farm�cias de manipula��o, onde atendemos com todos os dados cient�ficos?? necess�rios, sendo este o canal onde o produto est� sendo lan�ado comercialmente, posicionado como insumo para f�rmulas manipuladas�, detalha.
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